Mathilde WELLS
Number of publications : 57
2026
Scientific journals/Article
- Fauquet, J., Ellatiff, A., Palmieri, C., Duez, P., Blankert, B., Wells, M., & Nachtergael, A. (15 February 2026). Transposition of the Complementary Developing Solvent Technique to Flash Chromatography: A Structured Step-Based Fractionation Strategy for Complex Plant Extracts. "Journal of Separation Science, 49" (2), 70376. doi:10.1002/jssc.70376
2025
Scientific journals/Article
- Leveque, M., Wells, M., Beukens, D., Lefebvre, V., Hambye, S., & BLANKERT, B. (07 December 2025). Quantification of Interactions between Small Molecules and RNA Probes Representative of Myotonic Dystrophy Type 1 Using Affinity Capillary Electrophoresis and UPLC-UV. "ACS Omega, 10" (50), 62205-62215. doi:10.1021/acsomega.5c09840
Scientific congresses and symposiums/Unpublished conference/Abstract
- Wells, M., Hervé, A., Tiflit, A., Konare, D., Beukens, D., Genbauffe, A., Zubrzycki, S., Fougère, L., Blankert, B., & Destandau, E. (01 September 2025). "Revealing the bioactive potential of toad venom extracts through a bio-guided fractionation strategy using centrifugal partition chromatography" [Paper presentation]. 73rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Naples, Italy.
- Leveque, M., Wells, M., Hambye, S., Lefebvre, V., Beukens, D., & Blankert, B. (19 June 2025). "Quantification of affinity constants between pentamidine and pentamidine-like compounds with RNA probes representative of myotonic dystrophy type 1 by affinity capillary electrophoresis" [Paper presentation]. 54th International Symposium on High Performance Liquid Phase Separations & Related Techniques, Bruges, Belgium.
Scientific congresses and symposiums/Poster
- Fauquet, J., Wells, M., Karasiewicz, T., Duez, P., Blankert, B., & Nachtergael, A. (12 September 2025). "From Folk Remedy to Discovery: An HPLC-HRMS Untargeted Metabolomics Workflow Unveil Species-Specific Metabolites in Sideritis herba" [Poster presentation]. 27th Belgian Society for Mass Spectrometry Meeting, Mons, Belgium.
- Ghiande, L., Wells, M., Genbauffe, A., Journe, F., Lefebvre, V., Beukens, D., Karasiewicz, T., Leroy, B., Wattiez, R., & Blankert, B. (12 September 2025). "Development of a LC-MS/MS analysis method to quantify bufalin and marinobufagenin in plasma" [Poster presentation]. 27th Belgian Society for Mass Spectrometry Meeting, Mons, Belgium.
- Fauquet, J., Ellatiff, A., Palmieri, C., Duez, P., Blankert, B., Wells, M., & Nachtergael, A. (31 August 2025). "Systematic fractionation using complementary developing solvent technique in flash chromatography: a key step in dereplication strategies for natural products" [Poster presentation]. 73rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Naples, Italy.
- Leveque, M., Wells, M., Hambye, S., Lefebvre, V., Beukens, D., & Blankert, B. (17 June 2025). "Quantification of affinity constants between pentamdine and pentamidine-like compounds with RNA probes representative of myotonic dystrophy type 1 by affinity capillary electrophoresis" [Poster presentation]. 54th International Symposium on High Performance Liquid Phase Separations & Related Techniques, Bruges, Belgium.
- Wells, M., Hervé Alexandre, Tiflit Abdellah, Konare Djabou, Beukens, D., Genbauffe, A., Zubrzycki Sandrine, Fougère Laetitia, Michel Thomas, Blankert, B., & Destandau Emilie. (16 June 2025). "Bio-guided fractionation strategy by centrifugal partition chromatography to reveal the bioactive potential of toad venom extracts" [Poster presentation]. 54th International Symposium on High Performance Liquid Phase Separations & Related Techniques, Bruges, Belgium.
- Ghiande, L., Wells, M., Genbauffe, A., Lefebvre, V., Beukens, D., Karasiewicz, T., Leroy, B., Wattiez, R., & Blankert, B. (16 June 2025). "Development of a LC-MS/MS analysis method to quantify bufalin and marinobufagenin in plasma" [Poster presentation]. 54th International Symposium on High Performance Liquid Phase Separations & Related Techniques, Bruges, Belgium.
Dissertations and theses/Master’s dissertation
- DEFLANDRE, A. (2025). "L’effet des thérapies hormonales sur la santé cardiovasculaire des personnes transgenres" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/55137
- GHIANDE, L. (2025). "Optimisation de l'extraction de la bufaline et de la marinobufagénine d'échantillons plasmatiques" [Master’s dissertation, Université de Lille-Faculté de Pharmacie-UFR3S]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/54732
- AMRANE, A. (2025). "Techniques analytiques pour la détection de microplastiques dans l’environnement" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/55139
- Njanko Tchoujwen, P. (2025). "Etude de l’influence d’extraits de venins de crapauds sur la mélanogénèse : développement d’une méthode UPLC-Vis pour l’analyse de la mélanine dans les culots cellulaires" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/54733
- Boucetta, C. (2025). "Evaluation de l’impact de différents agents précipitants sur la liaison Bufaline-protéines plasmatiques" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/54674
- KENMOGNE, D. (2025). "Méthodes de dosage de l’hémozoïne comme outil diagnostique de la malaria" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/55141
- BECHICHI, D.-N. (2025). "Extraction des molécules bioactive en chimie verte" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/55140
Scientific conferences in universities or research centers/Scientific conference in universities or research centers
- Wells, M.* , & Nachtergael, A.*. (24 May 2025). "Étude de la disparité de genre dans la prise en charge de la douleur" [Paper presentation]. Journées d’études sur les questions de genre dans la recherche à l’UMONS, Mons, Belgium.
2024
Scientific journals/Article
- Delcorps, J., Rawat, K. S., Wells, M., Ben Ayed, E., Grignard, B., Detrembleur, C., Blankert, B., Gerbaux, P., Van Speybroeck, V., & COULEMBIER, O. (June 2024). Turning carbon dioxide into dialkyl carbonates through guanidinium-assisted SN2 ion-pair process. "Cell Reports. Physical Science, 5" (7), 102057. doi:10.1016/j.xcrp.2024.102057
- Soumoy, L., Genbauffe, A., Mouchart, L., Sperone, A., Trelcat, A., Mukeba-Harchies, L., Wells, M., Blankert, B., Najem, A., Ghanem, G., Saussez, S., & Journe, F. (04 January 2024). ATP1A1 is a promising new target for melanoma treatment and can be inhibited by its physiological ligand bufalin to restore targeted therapy efficacy. "Cancer Cell International, 24" (1), 8. doi:10.1186/s12935-023-03196-y
Scientific congresses and symposiums/Poster
- Fauquet, J., Karasiewicz, T., Wells, M., Duez, P., Blankert, B., & Nachtergael, A. (07 July 2024). "Dereplication strategy and purification of plant's active secondary metabolites through bio-guided fractionation, LC-(HR)MS and data mining" [Poster presentation]. MSBM XVI - 16th Mass Spectrometry School in Biotechnology and Medicine, Dubrovnik, Croatia.
- Wells, M., Crestin, I.-V., Beukens, D., & Blankert, B. (28 May 2024). "Development of a UHPLC-MS assay to evaluate 𝜷-hematin polymerization inhibition for the identification of new potential antimalarial candidates" [Poster presentation]. 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Leuven, Belgium.
Scientific conferences in universities or research centers/Scientific conference in universities or research centers
- Delcorps, J., Ben ayed, A., Wells, M., Gerbaux, P., & Coulembier, O.*. (26 January 2024). "Preparation of Dialkyl Carbonates through Unique Guanidinium-assisted SN2 Ion-Pair Process" [Paper presentation]. EDT-CHIM Scientific Day.
2023
Scientific journals/Article
- Wells, M., Hambye, S., & Blankert, B. (2023). Preliminary insight into the potential antiplasmodial activity and cytotoxicity of Bufo bufo and Incilius alvarius poison. "Toxicon, 227". doi:10.1016/j.toxicon.2023.107092
Dissertations and theses/Master’s dissertation
- BALQUEES, J. (2023). "Mesure du taux d'inhibition de la synthèse de bêta-hématine par LC-UV-VIS" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/54729
- CHAABAN, L. (2023). "Exploration de l'extraction par SPE/SLE du céfépime dans le plasma" [Master’s dissertation, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/54726
Scientific conferences in universities or research centers/Scientific conference in universities or research centers
- Wells, M., Hambye, S., & Blankert, B. (24 May 2023). "Du venin de crapaud aux composés antiplasmodiaux en un bond : Stratégies de fractionnement bio-guidé par chromatographie flash et CCM préparative" [Paper presentation]. Journée AFSEP Club Île de France - Prep, partez ! Le point sur la chromatographie préparative, Paris, France.
2022
Scientific journals/Article
- Wells, M., Fossepre, M., Hambye, S., Surin, M., & Blankert, B. (December 2022). Uncovering the antimalarial potential of toad venoms through a bioassay-guided fractionation process. "International Journal for Parasitology: Drugs and Drug Resistance, 20", 97 - 107. doi:10.1016/j.ijpddr.2022.10.001
Scientific congresses and symposiums/Unpublished conference/Abstract
- Wells, M., Hambye, S., & Blankert, B. (12 September 2022). "Development of a bioassay-guided fractionation protocol to unveil toad venoms as a new source of potential antimalarial candidates" [Paper presentation]. 12th International Symposium of Drug Analysis 32nd International Symposium on Pharmaceutical and Biomedical Analysis, Mons, Belgium.
Scientific congresses and symposiums/Paper published in a journal
- Loyez, M., Wells, M., Hambÿe, S., Hubinon, F., Blankert, B., Wattiez, R., & Caucheteur, C. (17 May 2022). PfHRP2 detection using plasmonic optical fibers: a step towards early malaria diagnosis. "Proceedings of SPIE: The International Society for Optical Engineering, 12139".
Scientific congresses and symposiums/Poster
- Soumoy, L., Wells, M., Najem, A., Krayem, M., Ghanem, G., Hambye, S., Saussez, S., Blankert, B., & Journe, F. (12 September 2022). "Uncovering the antiproliferative potential of toad venoms on metastatic melanoma" [Poster presentation]. 12th International Symposium of Drug Analysis 32nd International Symposium on Pharmaceutical and Biomedical Analysis, Mons, Belgium.
Dissertations and theses/Doctoral thesis
- Wells, M. (2022). "Development of a bioassay-guided fractionation protocol to unveil toad venoms as a new source of potential antimalarial candidates" [Doctoral thesis, UMONS - Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/44317
2021
Scientific journals/Article
- Loyez, M., Wells, M., Hambye, S., Hubinon, F., Blankert, B., Wattiez, R., & Caucheteur, C. (28 July 2021). PfHRP2 detection using plasmonic optrodes: performance analysis. "Malaria Journal, 20" (332).
Scientific congresses and symposiums/Unpublished conference/Abstract
- Wells, M., Hambye, S., & Blankert, B. (14 September 2021). "Identifying new potential antimalarial compound in toad venoms through a bio-guided fractionation process" [Paper presentation]. 1st Congress of the European Venom Network EUVEN.
Scientific congresses and symposiums/Poster
- Wells, M., Hambye, S., & Blankert, B. (05 October 2021). "Développement d'une stratégie de fractionnement bio-guidé pour l'identification de composés antiplasmodiaux issus de venins de Bufonidae" [Poster presentation]. 14ème Congrès Francophone sur les Sciences Séparatives et les Couplages de l'AFSEP, Paris, France.
Dissertations and theses/Master’s dissertation
- Van Bourgogne, N., Wells, M., Hambye, S., & Blankert, B. (2021). "Activité cytostatique et antiproliférative de composés de bas poids moléculaire issus de venins" [Master’s dissertation, Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/8343
2020
Scientific journals/Article
- Soumoy, L., Wells, M., Ahmad, N., Krayem, M., Ghanem, G., Hambye, S., Saussez, S., Blankert, B., & Journe, F. (2020). 'Toad Venom Antiproliferative Activities on Metastatic Melanoma: Bio-Guided Fractionation and Screening of the Compounds of Two Different Venoms'. "Biology", (9), 218-234.
Scientific congresses and symposiums/Unpublished conference/Abstract
- Wells, M., Hambye, S., & Blankert, B. (17 September 2020). "Discovery strategies for novel antiplasmodial compounds from the venom of Bufo toads" [Paper presentation]. Venoms and Toxins, Oxford, United Kingdom.
- Wells, M., & Soumoy, L. (03 February 2020). "Évaluation in vitro des activités antiprolifératives et cytotoxiques d'extraits de venins de crapauds sur des lignées cellulaires de mélanome" [Paper presentation]. Séminaire 'Kangourou' de l'Institut Santé, Mons, Belgium.
2019
Scientific journals/Article
- Baroni, A., Neaga, I., Delbosc, N., Wells, M., Verdy, L., Ansseau, E., Vanden Eynde, J.-J., Belayew, A., Bodoki, E., Oprean, R., Hambye, S., & Blankert, B. (25 September 2019). Bioactive Aliphatic Polycarbonates Carrying Guanidinium Functions: An Innovative Approach for Myotonic Dystrophy Type 1 Therapy. "ACS Omega, 4" (19), 18126 - 18135. doi:10.1021/acsomega.9b02034
- Lenaerts, C., Wells, M., Hambye, S., & Blankert, B. (17 January 2019). Marinobufagenin extraction from Rhinella marina toad glands: alternative approaches for a systematized strategy. "Journal of Separation Science, 42" (7), 1384 - 1392. doi:10.1002/jssc.201800879
Scientific congresses and symposiums/Unpublished conference/Abstract
- Wells, M., Soumoy, L., Journe, F., Saussez, S., Hambye, S., & Blankert, B. (04 December 2019). "Bio-guided fractionation for the isolation of antiplasmodial and cytotoxic compounds from the venom of Bufo toads" [Paper presentation]. 26ème RT-SFET, Paris, France.
- Wells, M. (24 May 2019). "Draw my PhD" [Paper presentation]. Journée de l'institut santé, Mons, Belgium.
- Wells, M., Van Koninckxloo-Van Bever, A., Hambye, S., & Blankert, B. (20 May 2019). "Extraction and characterization of potential new antimalarial compounds from toad venom" [Paper presentation]. 20th Forum of Pharmaceutical Sciences, Brussels, Belgium.
Scientific congresses and symposiums/Poster
- Wells, M., Hambye, S., & Blankert, B. (29 November 2019). "Fractionation process for the isolation of antiplasmodial compounds from the venom of Rhinella marina and Bufo bufo" [Poster presentation]. Bioforum, Liège, Belgium.
- Wells, M., Van Koninckxloo-Van Bever, A., Hambye, S., & Blankert, B. (05 March 2019). "Analysis and comparison of bufadienolide contents in the venoms of six different species of Bufo toads by High-Performance Thin-layer Chromatography" [Poster presentation]. Matinée des chercheurs (MdC 2019), Mons, Belgium.
Diverse speeches and writings/Article for a general audience
- Wells, M., Hambye, S., & Blankert, B. (2019). Du venin de crapaud pour soigner la malaria. "La Province".
2018
Scientific congresses and symposiums/Unpublished conference/Abstract
- Lenaerts, C., Wells, M., Hambye, S., & Blankert, B. (12 September 2018). "Quantification of endogenous marinobufagin by a high-specific and very sensitive UPLC-MS/MS assay in non-patological pregnancy and preeclampsia" [Paper presentation]. DA-PBA 2018 : 11th International symposium on Drug Analysis - 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, Belgium.
- Wells, M. (15 May 2018). "Extraction et caractérisation de nouveaux agents anti-malariques potentiels du venin de crapauds" [Paper presentation]. 1er Congrès PerScif - La parole aux jeunes chercheurs en FMP, Mons, Belgium.
Scientific congresses and symposiums/Poster
- Wells, M., Hambye, S., & Blankert, B. (10 September 2018). "Extraction and characterization of potential new antimalarial compounds from toads' venoms" [Poster presentation]. DA-PBA 2018 : 11th International symposium on Drug Analysis - 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, Belgium.
- Thi Nguyen, B.-L., Wells, M., Nachtergael, A., & Duez, P. (26 August 2018). "Cytotoxicity study of Equisetum diffusum D. Don., Glochidion eriocarpum Champ. ex Benth., Clerodendrum cyrtophyllum Turcz. collected in Northern Vietnam" [Poster presentation]. 66th Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Shanghai, China.
- Wells, M., Hambye, S., & Blankert, B. (12 July 2018). "Isolation and identification strategies of potential antimalarial components from toad venom (bufo marinus) using thin-layer chromatography" [Poster presentation]. 2nd International Symposium on Advances in Pharmaceutical Analysis, Lille, France.
- Wells, M., Hambye, S., & Blankert, B. (27 March 2018). "Isolation strategies of potential antiplasmodial compounds from Bufo toad venom" [Poster presentation]. Mardi des Chercheurs (MdC2018), Valenciennes, France.
Diverse speeches and writings/Article for a general audience
- Lepoutte, P., Blankert, B., & Wells, M. (2018). Le laboratoire frasnois Alphabiotoxine est renommé dans le monde entier. "L'Avenir".
2017
Scientific congresses and symposiums/Poster
- Wells, M., Lenaerts, C., Hambye, S., & Blankert, B. (28 March 2017). "Stratégies d'extraction et de purification de la Marinobufagénine à partir du venin du crapaud Bufo marinus" [Poster presentation]. 12ème Congrès de l'Association Francophone des Sciences Séparatives, Paris, France.
Dissertations and theses/Master’s dissertation
- Wells, M., Lenaerts, C., & Blankert, B. (2017). "Amélioration des techniques d'extraction de la marinobufagénine de matrices complexes" [Master’s dissertation, Université de Mons]. ORBi UMONS-University of Mons. https://orbi.umons.ac.be/handle/20.500.12907/9996
2016
Learning materials/Other
- Wells, M., Lenaerts, C., & Blankert, B. (2016). "Exploration et perfectionnement des techniques de purification de la Marinobufagénine à partir du venin de Bufo Marinus".